Aspirin ne sprecava srcane napade

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Aspirin ne sprecava srcane napade kod visoko rizicnih pacijenata

Uzimanje aspirina i antioksidanasa ne sprecava srcane napade kod visokorizicnih grupa pacijanata koji boluju od dijabetesa i asimptomaticnih arterijskih bolesti, sudeci po studiji koja je danas objavljena.

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Although there is considerable evidence showing no protective benefit of aspirin in high-risk patients without heart disease, guidelines are inconsistent and aspirin is commonly prescribed for the primary prevention of heart disease in patients with diabetes and with peripheral arterial disease.

Jill Belch, University of Dundee, Dundee, United Kingdom, and colleagues investigated whether aspirin and antioxidants given together or separately can reduce heart attacks and death in patients with diabetes and arterial disease.

The study included 1,276 patients aged over 40 years with diabetes and evidence of artery disease. Patients were randomised to receive either aspirin or placebo, an antioxidant or placebo, aspirin and antioxidant, or double placebo. Patients were followed over 8 years.

Overall, the researchers found no benefit from either aspirin or antioxidant treatment in the prevention of heart attacks or death. Patients in the aspirin groups had 116 primary events compared with 117 in the placebo group. No significant difference in events was seen between the antioxidant group and the placebo group.

The authors concluded by voicing their concern at the widespread prescribing of aspirin despite the lack of evidence to support its use in the primary prevention of heart attacks and death in people with diabetes and in view of its possible side effects.

In an accompanying editorial, William Hiatt, Colorado Prevention Center, Denver, Colorado, said: "These findings show that unlike statins and drugs for reducing hypertension, which have a benefit in all risk groups including those with and without heart disease, only patients with a history of clinical or symptomatic heart disease or stroke disease benefit from taking aspirin."

http://www.docguide.com/news/content.nsf/news/852571020057CCF6852574E5006894F4?OpenDocument&id=317AC309768BE86B8525727D004E4FE2&c=&count=10

[frckica-j]

Hm, eto ti belaj!!! ©ta je ovo, prvo vitamini B grupe po novoj studiji isto nisu spreèili stvrdnuæe arterija, a sad i aspirin... ©ta je sledeæe?