zbog cega estar u bocnom lancu deluje antikancerogeno?

Started by aziraphale, 12-09-2006, 14:54:56

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aziraphale

12-09-2006, 14:54:56
"...zbog prisustva cetvoroclanog oksetana i estarske funkcije u bocnom lancu, taksol poseduje antikancerogenu aktivnost."

zbog cega estar u bocnom lancu deluje antikancerogeno?

sandric

#1
12-09-2006, 21:26:35
dejstvo mu se zasniva na aklilovanju metabolita,na taj nacin deaktivira neoplazme

sandric

#2
12-09-2006, 21:41:18
dejsvo ispoljava samo oksetan jer on ucestvuje u alkilovanju tako bar tvrde oni sa farm.hemije

aziraphale

#3
13-09-2006, 00:22:36
ok, oksetan, to mogu da razumem, ali cemu onda  prica o estru?

Adonis_Vernalis

#4
14-09-2006, 10:23:27 Last Edit: 14-09-2006, 10:26:02 by Adonis_Vernalis
Mozda cete na ovim sajtovima pronaci bar delic odgovora?

http://www.21cecpharm.com/px/action.htm

http://www.usm.maine.edu/~newton/Chy251_253/Lectures/NaturalProducts/Taxol.html
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